(S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid

(S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid - Names and Identifiers

Name	(S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid
Synonyms	BOC-S-PIPAZ(FMOC)-OH 1-BOC-4-FMOC-PIPERAZINE-2-(S)-CARBOXYLIC ACID (S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid (S)-1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID (2s)-1,2,4-piperazinetricarboxylic acid 1-(tert-butyl) 4-(9h-fluoren-9-ylmethyl) ester (S)-N1-T-BUTYLOXYCARBONYL-N4-(9-FLUORENYLMETHYLOXYCARBONYL)-PIPERAZINIE-2-CARBOXYLIC ACID (S)-PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER (S)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-1-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID (2S)-1-[(tert-butoxy)carbonyl]-4-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperazine-2-carboxylic acid (2S)-4-(9H-fluoren-9-ylmethoxycarbonyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid
CAS	1034574-30-5
InChI	InChI:1S/C25H28N2O6/c1-25(2,3)33-24(31)27-13-12-26(14-21(27)22(28)29)23(30)32-15-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,20-21H,12-15H2,1-3H3,(H,28,29)

(S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C25H28N2O6
Molar Mass	452.5
Density	1.292±0.06 g/cm3(Predicted)
Boling Point	624.4±55.0 °C(Predicted)
Flash Point	331.4 °C
pKa	3.68±0.20(Predicted)
Storage Condition	2-8℃

(S)-1-N-Boc-4-N-Fmoc-piperazine 2-carboxylic acid - Introduction

(S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid is an organic compound. Its properties are as follows:

1. Appearance: A white to light yellow solid.
2. Solubility: Soluble in organic solvents such as chloroform and dimethyl sulfoxide.
3. molecular formula: C24H27N3O5.
4. Molecular weight: 437.49g/mol.

There are two main uses of this compound:
1. As an intermediate in the synthesis of organic compounds: Because of its protecting group (Boc and Fmoc), it can be used as a protecting group in organic synthesis to protect the reactivity of other functional groups in the target compound. In addition, it can also be used as a starting material for the synthesis of other organic compounds.
2. Used in protein chemistry: Due to the piperazine-2-carboxylic acid structure in this compound, it can be used as a protecting group in the field of protein chemistry. In the synthesis of peptides and proteins, it is capable of protecting amino groups in amino acid residues.

Methods of preparing (S)-1-N-Boc-4-N-Fmoc-piperazine-2-carboxylic acid are generally accomplished by synthetic chemical methods. The specific preparation steps may include the reaction of piperazine-2-carboxylic acid and the corresponding protecting agent (Boc and Fmoc), solvent extraction, crystallization purification and the like.

Regarding the safety information of the compound, the following points should be noted: The compound may cause irritation to the eyes, skin and respiratory tract, so appropriate protective measures should be taken when using.
2. During the preparation process, pay attention to avoid contact with the dust and solution of the compound.
3. Keep the laboratory well ventilated and avoid inhaling the vapors of the compound.
4. when using, pay attention to follow the safety procedures, and use personal protective equipment, such as laboratory gloves, protective glasses, etc.
5. When storing and handling the compound, it should be kept in a sealed container, away from fire, heat and light to avoid unnecessary accidents.

Last Update：2024-04-10 22:29:15